Staying Healthy with G6PD Deficiency: A valuable reference guide for eating safely

Staying Healthy with G6PD Deficiency: A valuable reference guide for eating safely
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Staying Healthy with G6PD Deficiency: Valuable reference guide for eating safely

G6PD deficiency can be detected via several methods, the most common being a quantitative laboratory assay for G6PD enzyme activity. Visibility Others can see my Clipboard. Your browser is currently not set to accept cookies. National Library of Medicine. My brother has glucose 6 phosphate dehydrogenase G6PD deficiency. A guide and cookbook for staying healthy with G6PD Deficiency.

G6PD is the rate-limiting enzyme in the pentose phosphate pathway. Thus, deficiency of the G6PD enzyme results in reduced glutathione making the red cells vulnerable to oxidative damage and thus liable to haemolysis. The disease is X-linked with about variants reported. Most of the variants occur sporadically and are single amino acid defects in a protein of amino acids. The extent of haemolysis may vary across individuals, due to genetic heterogeneity.

Despite this the extent of haemolysis is dose-dependent. Most people with G6PD deficiency have a normal life expectancy despite a predisposition to neonatal jaundice and sensitivity to certain drugs.

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If neonatal jaundice is not energetically treated, there may be a hidden risk for kernicterus. There is no definite association between G6PD deficiency and susceptibility to cataracts. Although the disease is thought to be fairly benign, where enzyme levels are severely deficient there can be inadequate leukocyte function also. This results in chronic granulomatous disease. In Saudi Arabia the G6PD status of all children aged 1 month to 14 years, who were treated for meningitis, septicaemia, osteomyelitis, or typhoid fever during a nine-year period, was reviewed.

The observed frequency of G6PD deficiency was significantly higher than expected for the entire group, for females with both catalase-positive and catalase-negative infection, and for males with catalase-positive infections. Am Fam Physician. Kaplan M, Hammerman C ; Glucosephosphate dehydrogenase deficiency: a hidden risk for kernicterus. Semin Perinatol. Mesner O, Hammerman C, Goldschmidt D, et al ; Glucosephosphate dehydrogenase activity in male premature and term neonates. Murki S, Dutta S, Narang A, et al ; A randomized, triple-blind, placebo-controlled trial of prophylactic oral phenobarbital to reduce the need for phototherapy in G6PD-deficient neonates.

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Caring for Glucose-6-Phosphate Dehydrogenase (G6PD)–Deficient Patients: Implications for Pharmacy

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See our disclaimer. A one-of-a-kind guide book with tips and recipes to help people and their families minimize the negative effects of G6PD Deficiency. This book includes food and vitamin recommendations to help build red blood cells. It also includes an extensive list of foods and food additives to avoid which are known to cause oxidative stress.

There are instructions on how to make your favorite recipes safe, as well as tips on feeding infants and children with G6PDD. There are over recipes included in the book which we think may just become some of your family's favorites.